Primal Health Databank: Study
| Entry No: | 0092 |
| Title: | Fetal and infant growth and cardiovascular risk factors in women |
| Author(s): | Fall CHD, Osmond C, Barker DJP, et al. |
| Reference: | BMJ 1995; 310: 428-32 |
| Place of Study: | Hertfordshire, England |
| Abstract: | The objective of the study is to examine whether cardiovascular risk factors in women are related to fetal and infant growth. 297 women born in 1923-30 and still living in East Hertfordshire were followed up. Their birth weight and weight at one year were recorded. The main outcome measures were plasma glucose and insulin concentrations during glucose tolerance test; blood pressure; fasting total low density lipoprotein, high density lipoprotein cholesterol, trigyceride, apolipoprotein A I and B, plasma fibrinogen and factor VII concentrations. The highest values of coronary risk factors occur in people who were small at birth and became obese. In contrast with men, low rates of infant growth did not predict levels of risk factors in women. |
| Keyword(s): | birth weight, Blood pressure, Cardiovascular disease, coronary heart disease |
| Discussion: | As in many studies relating an adult condition to birth size, birth order has not been taken into consideration. Yet birth order is the best known single factor influencing birth weight. For example according to a British calculation the average difference in birth weight between first born and second born children is 138 grams. (see Odent M., Tsujino J., Studies exploring health in relation to intrauterine life should look at birth order, BMJ 1997; 314:1416) |
| See Also: | No related entries mentioned for this entry |
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