Primal Health Databank: Study
| Entry No: | 0411 |
| Title: | Haloperidol-related dyskinesias and pre- and perinatal complications in autistic children |
| Author(s): | Armenteros JL, Adams PB, Campbell M, Eisenberg ZW, Kerr B, Hersh JH, Dean JC |
| Reference: | Psychopharmacol Bull 1995;31(2):363-9 |
| Place of Study: | USA |
| Abstract: | It has been hypothesized that an association exists between pre- and perinatal complications, central nervous system (CNS) dysfunction, and the development of tardive (TD) and withdrawal dyskinesias (WD). We assessed the relationship between pre- and perinatal complications and TD/WD in a sample of 118 children with autism who participated in an ongoing long-term prospective study of the efficacy and safety of haloperidol. Anesthesia during delivery was more frequent in children who developed TD/WD (25 of 40, 62.5%) than in those who did not (30 of 78, 38.5%) (p = .019). Six of 7 males with short labor developed TD/WD (p = .007). Pre- and perinatal complications appear to be related to the development of TD/WD in this sample of children. |
| Keyword(s): | autism, autistic spectrum disorder, birth complications, head circumference, labor induction, labour induction, obstetric medication, preeclampsia, Rhesus-immunization |
| Discussion: | No discussion mentioned for this entry |
| See Also: | No related entries mentioned for this entry |
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