Primal Health Databank: Study

Entry No:0484
Title:Birth weight, weight at 1 y of age, and body composition in older men: findings from the Hertfordshire Cohort Study
Author(s):Sayer AA, Syddall HE, Dennison EM, Gilbody HJ, Duggleby SL, Cooper C, Barker DJP, Phillips DI
Reference:Am J Clin Nutr. 2004 Jul;80(1):199-203
Place of Study:UK
Abstract:The authors investigated the associations of birth weight and weight at 1 y of age with body composition in older men. They carried out a retrospective cohort study in Hertfordshire, United Kingdom. Men who were born between 1931 and 1939 and for whom there were records of birth weight and weight at 1 y of age (n = 737) participated in the study. The main outcome measures were adult body mass index, fat-free mass, and fat mass. Birth weight was significantly and consistently positively associated with adult body mass index and fat-free mass but not with measures of adult fat mass. In contrast, weight at 1 y of age was associated with adult body mass index, fat-free mass, and fat mass. The authors conclude that the consistently reported positive relation between birth weight and adult body mass index may reflect prenatal and maternal influences on fat-free mass rather than on fat mass in older people. The postnatal environment may be more influential than prenatal factors in the development of obesity in later life.
Keyword(s):birth weight, body mass index, obesity, postnatal environment
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