Primal Health Databank: Study
| Entry No: | 0568 |
| Title: | Birth month and sensitization to house dust mites in asthmatic children |
| Author(s): | Yoo Y, Yu J, Kang H, Kim DK, Koh YY, Kim CK |
| Reference: | Allergy. 2005 Oct;60(10):1327-30 |
| Place of Study: | Korea |
| Abstract: | The aim of this study was to investigate whether birth month patterns differ for asthmatic patients sensitized only to house dust mites (HDMs) and for those sensitized to HDMs and other allergen(s). Among 2225 patients with asthma, aged 10-16 years, 1642 sensitized to HDMs were identified by skin prick testing. This group was composed of patients sensitized only to HDMs (n = 715) and patients sensitized to HDMs and other allergen(s) (n = 927). The birth month distributions of the group of HDM-sensitive asthmatics or its subgroups were compared with that of a reference population (total live births in the same years as the studied subjects). The risk ratio of a given birth month in relation to all the other months was calculated as an odds ratio (OR) with the corresponding 95% confidence interval (CI). A significant difference in birth month distribution was observed for HDM-sensitive asthmatics (chi(2) = 23.6, P = 0.015), with higher rates of birth in August (OR: 1.23, 95% CI: 1.04-1.46) and September (1.24, 1.04-1.46). When the two subgroups were analyzed separately, significantly more births were noted in August (1.34, 1.06-1.71) and September (1.34, 1.05-1.70) for those sensitized only to HDMs, whereas no such birth month preference was observed for those sensitized to HDMs and other allergen(s).
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| Keyword(s): | allergy, asthma, house dust mites, seasonality of birth |
| Discussion: | No discussion mentioned for this entry |
| See Also: | No related entries mentioned for this entry |
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