Primal Health Databank: Study
| Entry No: | 0722 |
| Title: | Maternal Rh D status, anti-D immune globulin exposure during pregnancy, and risk of autism spectrum disorders |
| Author(s): | Croen LA, Matevia M, Yoshida CK, Grether JK, Joner G; Norwegian Childhood Diabetes Study Group, Stuver SO, Hsieh C |
| Reference: | Am J Obstet Gynecol. 2008 Sep;199(3):234.e1-6. Epub 2008 Jun 13 |
| Place of Study: | USA |
| Abstract: | Case-control study among children born from 1995 to 1999 at Kaiser Permanente Northern California hospitals. Cases (n = 400) were children with an autism diagnosis; controls (n = 410) were children without autism, randomly sampled and frequency matched to cases on sex, birth year, and birth hospital. Maternal Rh D status and anti-D immune globulin exposure were ascertained from prenatal medical records. RESULTS: No case-control differences were observed for maternal Rh negative status (11.5% vs 10.0%, P = .5) or prenatal anti-D immune globulin exposure (10.0% vs. 9.3%, P = .7). Risk of autism remained unassociated with maternal Rh status or prenatal exposure to anti-D immune globulins after adjustment for covariates. CONCLUSION: These data support previous findings that prenatal exposure to thimerosal-containing anti-D immune globulins does not increase the risk of autism. |
| Keyword(s): | autism, autistic spectrum disorder, labour induction, pre-eclampsia, preeclampsia, Rh incompatibility, Rhesus-immunization, Rhesus-immunization, vaccination |
| Discussion: | No discussion mentioned for this entry |
| See Also: | No related entries mentioned for this entry |
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